2020

1) PDE6D Inhibitors with a New Design Principle Selectively Block K-Ras Activity, Siddiqui, F.A., Alam, C., Rosenqvist, P., Ora, M., Sabt, A., Manoharan, G.B., Bindu, L., Okutachi, S., Catillon, M., Taylor, T., Abdelhafez, O.M., Lönnberg, H., Stephen, A.G., Papageorgiou, A.C., Virta, P., Abankwa, D. ACS Omega 2020, 5(1), pp. 832–842

2) 1,8-Dimercuri-6-Phenyl-1H-Carbazole as a Monofacial Dinuclear Organometallic Nucleobase, Ukale, D.U., Tähtinen, P., Lönnberg, T. Chemistry – A European Journal, pp. 2164–2168

3) Nucleotide Sugars in Chemistry and Biology Mikkola, S. Molecules (Basel, Switzerland), 2020, 25(23)

4) Kinetic and NMR spectroscopic study of the chemical stability and reaction pathways of sugar nucleotides Jaakkola, J., Nieminen, A., Kivelä, H., Korhonen, H., Tähtinen, P., Mikkola, S. Nucleosides, Nucleotides and Nucleic Acids, 2020

5) The detection of solid phosphorus and fluorine in the dust from the coma of comet 67P/Churyumov-Gerasimenko Gardner, E., Lehto, H.J., Lehto, K., …Cottin, H., Hilchenbach, M. Monthly Notices of the Royal Astronomical Society, 2020, 499(2), pp. 1870–1873

6) Immobilized Carbohydrates for Preparation of 3′-Glycoconjugated Oligonucleotides Österlund, T., Aho A., Äärelä, A., Tähtinen, V., Korhonen, H., Virta, P. Current Protocols in Nucleic Acid Chemistry, 2020, 83(1), e122

7) Metal-Mediated Base Pairing of Rigid and Flexible Benzaldoxime Metallacycles Maity, S., Hande, M., Lönnberg, T. ChemBioChem, 2020, 21(16), pp. 2321–2328

8) Site-Specific Linking of an Oligonucleotide to Mono- And Bivalent Recombinant Antibodies with SpyCatcher-SpyTag System for Immuno-PCR Kushnarova-Vakal, A., Äärelä, A., Huovinen, T., Virta, P., Lamminmäki, U. ACS Omega, 2020, 5(38), pp. 24927–24934.

9) Conjugation of oligonucleotides to peptide aldehydes via a pH-responsive N-methoxyoxazolidine linker Aho, A., Sulkanen, M., Korhonen, H., Virta, P. Organic Letters, 2020, 22(17), pp. 6714–6718.

10) Mercury(II)-catalyzed cleavage, isomerization and depurination of RNA and DNA model compounds and desulfurization of their phosphoromonothioate analogs Saleh, L.Y., Ora, M., Lönnberg, T. Catalysts, 2020, 10(2), 219

11) Covalently Mercurated Molecular Beacon for Discriminating the Canonical Nucleobases Aro-Heinilä, A., Lönnberg, T., Virta, P. ChemBioChem, 2020, https://doi.org/10.1002/cbic.202000575

12) Pdedelta inhibitors Abankwa, D., Ora, M., Virta, P. PCT Int. Appl. (2020), WO 2020225285 A1 20201112.