2017

 

1) Zinc Ion-Dependent peptide nucleic acid-based artificial enzyme that cleaves RNA-Bulge size and sequence dependence, Murtola, M., Ghidini, A., Virta, P., Strömberg R. Molecules, 2017, 22, 1856.

2) Synthesis of oligonucleotides on a soluble support, Lönnberg Harri, Beilstein J. Org. Chem. 2017,  13,  1368.

3) Discovery of the Showdomycin Gene Cluster from Streptomyces showdoensis ATCC 15227 Yields Insight into the Biosynthetic Logic of C-Nucleoside Antibiotics. Palmu, K., Rosenqvist, P., Thapa, K., Ilina, Y., Siitonen, V., Baral, B., Mäkinen, J., Belogurov, G., Virta P., Niemi, J., Metsä-Ketelä, M. ACS Chem. Biol., 2017, 12 (6), pp 1472–1477. DOI: 10.1021/acschembio.7b00078.

4) Synthesis and Deprotection of Biodegradably and Thermally Protected Dinucleoside-2′,5′-Monophosphate Prodrug Model of 2-5A. Kiuru, E., Malmikare, S., Ora M. Chemistry & Biodiversity, 2017, DOI: 10.1002/cbdv.201700220.

5) Synthesis of Aminoglycoside-2′-O-Methyl Oligoribonucleotide Fusions. Granqvist, L., Kraszewski, A., Tähtinen V., Virta P. Molecules 2017, 22(5), 760; doi:10.3390/molecules22050760

6) 19F NMR Spectroscopic Analysis of the Binding Modes in Triple-Helical Peptide Nucleic Acid (PNA)/MicroRNA Complexes. Tähtinen V., Granqvist L., Murtola M., Strömberg R., Virta P. Chem Eur. J. 2017, DOI: 10.1002/chem.201700601

7) Fluorescent Oligonucleotide Probes for Screening High-Affinity Nucleobase Surrogates. Aro-Heinilä A., Lönnberg T. Chem Eur. J. 2017, 23, 1028.

8) Sulfurization of H-Phosphonate Diesters by Elemental Sulfur under Aqueous Conditions. Lönnberg T.  ACS Omega 2017, 2, 5122. https://pubs.acs.org/doi/abs/10.1021/acsomega.7b00970