Prof. Pasi Virta, Group Leader
Pasi Virta became professor of Organic Chemistry at Department of Chemistry, University of Turku 1.9.2016.
Main interests: Synthesis of biomolecular conjugates (oligonucleotides, carbohydrates and peptides), Transitions of higher order secondary structures of oligonucleotides, Biodistribution studies of oligomeric biomolecules, DNA-templated ligation, DNA-templated glycosylation, Glycosylation in aquosus media, Chemical modification of rare nucleosides.
Ass. Prof. Tuomas Lönnberg
Tuomas Lönnberg was appointed Assistant Professor of Organic Chemistry at the Department of Chemistry, University of Turku in Oct 2016.
Main research interests: Synthesis and properties of oligonucleotides incorporating organometallic nucleobase surrogates, Metal mediated base pairing, Mechanisms of biologically relevant phosphate-transfer reactions.
Dr. Jianwei Li, Independent Group leader of Molecular Systems Engineering
Dr. Jianwei Li started his independent career funded by Turku Collegium for Science and Medicine (TCSM) as a senior researcher at Department of Chemistry, University of Turku. In the following years, he will be leading a group to play the interface between systems chemistry and other emerging fields such as materials chemistry, enzymology and biology. For more details, please refer to our independent group page www.li-chemlab.com
Senior lecturer, Dr. Satu mikkola
Satu Mikkola has been working as a senior lecturer in organic chemistry since 2001. She is also currently appointed as the deputy head of the Department of Chemistry being in charge of teaching matters.
Main interests: Dr. Mikkola has long worked on mechanisms and kinetics of hydrolytic reactions of RNA, related phosphodiesters and other biological phosphates, such as dinucleoside oligophosphates and sugar nucleotides.
Senior lecturer, Dr. Mikko Ora
Mikko Ora has worked as Senior lecturer at Department of Chemistry, University of Turku since 2006.
Main interests: Prodrug strategies of nucleotides and biologically active phosphate esters as goal to develop the degradable lipophilic carriers, the protecting groups, which are used to improve the cellular membrane penetration. The kinetic studies of the prodrugs to obtain mechanistic information on the chemical hydrolysis and enzymatic cleavage of the protecting groups. Syntheses of structurally modified nucleoside analogues.
Senior lecturer, Dr. Heidi Korhonen
Heidi Korhonen has worked as a University lecturer at the Department of Chemistry, University of Turku since autumn 2006. Currently she is working as a Senior lecturer.
Main interests: Mechanistic studies, including metal-ion catalyzed reactions, of RNA phosphodiester bond and other biologically active phosphate esters. Nucleoside phosphorylation. Enzyme-free, DNA-templated ligation reactions.
University lecturer, Dr. Tuomas Karskela
Tuomas Karskela has worked in various positions at the Department of Chemistry, University of Turku since spring 2000. Currently he is working as a University lecturer.
Main interests: Prebiotic formation of peptides, solid phase synthesis and peptide chemistry.
Researcher, Dr. Sajal Maity
Sajal Maity has been working as postdoctoral researcher in Bio-organic group at the Department of Chemistry, University of Turku, since December 2014. Presently he is working on the synthesis of metal incorporated oligonucleotides and studying the physicochemical properties of such oligonucleotides.
Main research interests: Synthesis and properties of oligonucleotides incorporating palladated nucleobase surrogates, Synthesis of carbohydrate conjugates.
Researcher, Dr. Yu Cao
Yu Cao, exploring biomaterials emerging from Dynamic Combinatorial Libraries (DCC), has been working as a postdoctoral fellow in Bio-organic group at the department of chemistry, University of Turku since May 2017.
Main interests: design and synthesis of different building blocks and templates for DCC system, and its application in biology, such as drug delivery and bionics.
Ms. Yonglei Lyu Research interests: see Molecular Systems Engineering Group
Ms. Yue Liang Research interests: see Molecular Systems Enginering Group
Ms. Lotta Granqvist, MSc Research interests: Characterization of higher order secondary structures of oligonucleotides by 19F NMR spectroscopy and development of novel 19F NMR probes for the detection
Mr. Ville Tähtinen, MSc Research interest: Development of high affinity triplex-forming probes for double helical nucleic acids, including aminoglycoside conjugates and chiral triplex forming PNAs, 19F NMR detection of triple helical RNA and DNA complexes.
Mr. Petja Rosenqvist, MSc Research ineterests: Chemical modification of rare C-nucleosides produced by soil bacteria, small molecular anti-cancer drugs
Mr. Chunfeng Chen Research interests: see Molecular Systems Enginering Group
Ms. Madhuri Hande Research interests: Synthesis and properties of oligonucleotides incorporating organometallic nucleobase surrogates, Metal mediated base pairing, in vivo-PET imaging of oligonucleotide conjugates
Mr. Dattatraya Ukale Research interest: Synthesis and properties of oligonucleotides incorporating organometallic nucleobase surrogates, Metal mediated base pairing (in particular Hg-mediated systems), NMR-spectroscopy.
Mr. Asmo Aro-Heinilä Research interest: Synthesis and properties of oligonucleotides incorporating organometallic nucleobase surrogates, high affinity metal mediated 19F NMR-probes
Mr. Vijay Gulumkar Reserach interests: Synthesis of oligonucleotide carbohydrate conjugates, in vivo-PET imaging of of oligonucleotide conjugates, small DNA-based self-asembled constructs assisteed by reversible and irreversible covalent cross-linkages and their drug delivery applications
Ms. Marika Karskela, MSc Research interests: Synthesis of oligonucleotide ccarbohydrate conjugates
Mr. Vyacheslav Kungurtsev, MSc Research interests: Large sacle liquid phase synthesis of oligonucleotides