2017

1) Discovery of the Showdomycin Gene Cluster from Streptomyces showdoensis ATCC 15227 Yields Insight into the Biosynthetic Logic of C-Nucleoside Antibiotics. Palmu, K., Rosenqvist, P., Thapa, K., Ilina, Y., Siitonen, V., Baral, B., Mäkinen, J., Belogurov, G., Virta P., Niemi, J., Metsä-Ketelä, M. ACS Chem. Biol., 2017, 12 (6), pp 1472–1477. DOI: 10.1021/acschembio.7b00078.

2) Synthesis and Deprotection of Biodegradably and Thermally Protected Dinucleoside-2′,5′-Monophosphate Prodrug Model of 2-5A. Kiuru, E., Malmikare, S., Ora M. Chemistry & Biodiversity, 2017, DOI: 10.1002/cbdv.201700220.

3) Synthesis of Aminoglycoside-2′-O-Methyl Oligoribonucleotide Fusions. Granqvist, L., Kraszewski, A., Tähtinen V., Virta P. Molecules 2017, 22(5), 760; doi:10.3390/molecules22050760

4) 19F NMR Spectroscopic Analysis of the Binding Modes in Triple-Helical Peptide Nucleic Acid (PNA)/MicroRNA Complexes. Tähtinen V., Granqvist L., Murtola M., Strömberg R., Virta P. Chem Eur. J. 2017, DOI: 10.1002/chem.201700601

5) Fluorescent Oligonucleotide Probes for Screening High-Affinity Nucleobase Surrogates. Aro-Heinilä A., Lönnberg T. Chem Eur. J. 2017, 23, 1028.